Clindamycin 1) Chemical Name: * methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate) 2) Drug name and master: * The dose name is Cleocin. Clindamycin is manufactured by several impertinent companies which include Teuto, Ranbaxy, and Stiefel. 3) Mechanism of Action: * Clindamycin is employ to wield sedate infections ca intentd by anaerobic bacteria. Clindamycin is withal prescribed to treat malignant infections due to strains of streptococci, pneumococci, and staphylococci. Clindamycin is an anti-parasitic drug that is prescribed to treat toxoplasmosis. Also, often it is utilize as investigational treatment for active PCP pneumonia. It alike treats respiratory tract infections. If you are allergic to penicillin, or should non use penicillin fit in to a medical student, then clindamycin should be use specifically for these patients. Due to a risk of colitis, acco rding to the warning on the prescription, a doctor should choose other less cyanogenic alternatives if the infection isnt as serious. An example would be erythromycin. To lessen the cherish the sustainability of Cleocin, it should lone(prenominal) be used to reanimate or go on infections and fungi that are definitely caused by vulnerable bacteria. 4) set apart or encompassing Spectrum: Narrow Spectrum 5) What organisms is this antibiotic for? * Aerobic positive cocci, including: staphylococcus aureus, Staphylococcus epidermidis, when tested by in vitro methods close to staphylococcal strains primitively resistant to erythromycin rapidly cause resistance to clindamycin, streptococcus (except Streptococcus faecalis), Pneumococci. * anaerobic gram-negative bacilli, including: genus Bacteroides species (including Bacteroides fragilis class and Bacteroides melaninogenucus group), Fusobacterium species. * Anaerobic gram-positive non spore forming bacilli, including: Pro pionibacterium, Eubacterium, Actinomyces spe! cies. Anaerobic and microaerophilic gram-positive cocci, including: Peptococcus species, Peptostreptococcus species, Microaerophilic streptococci. 6) How is it administered? Clindamycin give the bounce be administered in 3 mixed steps. Also, for the best results, think to take the antibiotic on a daily basis. * orally Take either with a meal or without a meal. Remember that if you are experiencing stomach pains, take with food. Taking it with a full glass of water is also optional. * Vaginal finish - demarcation that the cream can only be used in this area. It may cause burning, and above all do not have sexual intercourse while use this drug. * peel off Application Not to be taken by mouth. Lotion should be agitate prior to application. subscribe to pledget from foil and immediately throw away. take proper hygiene and wash hands before and afterward use. Apply only a thin strip of jelly to avoid irritation. Bandages, make-up, etc should not be applied until consulting a doctor for advice. 7) Any toxicities, or side effects? Â Â Â Â Â Â Â Â Abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting and diarrhea.
generalized subdued to moderate morbilliform-like (maculopapular) skin rashes, Vesiculobullous rashes, urticaria, have been find during drug therapy. idealistic instances of erythema muttiforme, some resembling Stevens-Johnson syndrome, and a few cases of anaphylactoid reactions have also been reported. rancor and abnormalities in liver function tests have been observed during clindamycin therapy. ephemeral neutropenia (leukopenia) and eosinophilia have been reported. Clindamycin has been shown to have neurom uscular blocking properties that may raise the actio! n of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Opposition has been corroborate between clindamycin and erythromycin. Do not take these antibiotics at the aforesaid(prenominal) time. References: 1) Retrieved February 22, 2006, from MedlinePlus Drug education net situation: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682399.html#brand-names 2) Retrieved February 22, 2006, from ADAP drugs Web set: http://www.atdn.org/access/drugs/clin.html 3) Retrieved February 22, 2006, from clindamycin usually used music for HIV & AIDS patients Web place: http://www.hivdent.org/drugs/clindamycin.htm 4) Retrieved February 22, 2006, from medicament instructions for clindamycin Web site: http://www1.va.gov/visn10/CincyMedSheets/Clindamycin.htm 5) Retrieved February 22, 2006, from Clindamycin Web site: http://www.clindamycin.com/ If you want to get a full essay, enunc iate it on our website:
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